On Tuesday, September 7, PCORI's Online System will open for the submission of Letters of Intent (LOIs) and applications for nine PCORI Funding Announcements (PFAs).

Among them are three Targeted PFAs that will seek research study proposals relating to healthy aging, osteoporotic fractures, and migraine prevention. Learn more here

There will also be opportunities for research proposals through the Cycle 3 Broad and Improving Methods PFAs under our current national priorities for research, and the Phased Large Awards for Comparative Effectiveness Research PFA.

LOIs for these PFAs are due Tuesday, October 5 by 5:00pm ET.

Register now for Virtual Applicant Town Halls related to these PFAs: View dates/times

PCORI will also be accepting proposals for three Implementation PFAs (for PCOR results, effective shared decision making approaches, and findings from PCORI's major research investments). LOIs are due Tuesday, September 28 by 5:00pm ET.

View all nine PFAs below for more details, including specific LOI and application submission deadlines.