Several PCORI Funding Announcements (PFAs) for 2021 will open on January 5. The Broad PFA seeks proposals for comparative clinical effectiveness research projects aligned with our priority areas for research. PCORI will also accept proposals for studies on improving methods to conduct patient-centered outcomes research and implementing PCORI-funded research results. Additionally, the first PCORI Pragmatic Clinical Studies PFA since 2018 will open. Letters of Intent for these opportunities are due in late January or early February, depending on the PFA. 

To be able to better assist you in planning, see all the 2021 opportunities currently listed:

Opening Tuesday, January 5, 2021

Broad PCORI Funding Announcements -- Cycle 1 2021 Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes -- Cycle 1 2021 Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 1 2021 Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results – Cycle 1 2021 Broad PCORI Funding Announcements -- Cycle 2 2021 Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 2 2021 Upcoming Broad PFA -- Cycle 3 2021 Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 3 2021

Opening Tuesday, May 4, 2021

Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results – Cycle 2 2021 Implementation of Effective Shared Decision Making Approaches in Practice Settings -- Cycle 2 2021 Upcoming Initiative -- Cycle 2 2021

Opening Tuesday, September 7, 2021

Phased Large Awards for Comparative Effectiveness Research -- Cycle 3 2021 Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results – Cycle 3 2021