CPRIT announces the release of five (5) RFAs for the Academic Research program. This is includes the NEW Individual Investigator Research Awards for Computational Systems Biology of Cancer. Complete RFAs and instructions detailing applicable deadlines and requirements are available in the Funding Opportunities section of CPRIT’s website.
***These RFAs are limited to only one per funding cycle. PIs are also limited by active prior CPRIT awards. Any questions about these limits should be directed to your pre-award analyst.***
The application period is: March 4, 2020 through June 3, 2020.
Individual Investigator Research Awards
Supports applications for innovative research projects addressing critically important questions that will significantly advance knowledge of the causes, prevention, and/or treatment of cancer. Areas of interest include laboratory research, translational studies, and/or clinical investigations. Competitive renewal applications accepted.
Individual Investigator Research Awards for Cancer in Children and Adolescents
Supports applications for innovative research projects addressing questions that will advance knowledge of the causes, prevention, progression, detection, or treatment of cancer in children and adolescents. Laboratory, clinical, or population-based studies are all acceptable. CPRIT expects the outcome of the research to reduce the incidence, morbidity, or mortality from cancer in children and/or adolescents in the near or long term. Competitive renewal applications accepted.
Individual Investigator Research Awards for Clinical Translation
Supports applications which propose innovative clinical studies that are hypothesis driven and involve patients enrolled prospectively on a clinical trial or involve analyses of biospecimens from patients enrolled on a completed trial for which the outcomes are known. Areas of interest include clinical studies of new or repurposed drugs, hormonal therapies, immune therapies, surgery, radiation therapy, stem cell transplantation, combinations of interventions, or therapeutic devices.
Individual Investigator Research Awards for Computational Systems Biology of Cancer
Supports applications for innovative mathematical and/or computational research projects addressing questions that will advance current knowledge in the (a) mechanisms that tie altered gene expression and downstream molecular mechanisms to functional cancer phenotypes and/or (b) mechanisms that tie tumor morphology to functional cancer phenotypes, and/or (c) mechanisms that tie treatment sequence and combination to evolving functional cancer phenotypes (that emerge as a result of treatment selection). Broadly speaking, functional cancer phenotypes include migratory, proliferative, metabolic and resistant cancer cell phenotypes.
Partnering of mathematical or computational scientists with cancer biologists or oncologists is highly recommended to form a truly interdisciplinary team that can both develop and validate models leading to a deeper integrated understanding of cancer progression and treatment.
Individual Investigator Research Awards for Prevention and Early Detection
Supports applications for innovative research projects addressing questions that will advance knowledge of the causes, prevention, early-stage progression, and/or early detection of cancer. Research may be laboratory-, clinical-, or population- based, and may include behavioral/intervention, dissemination or health services/outcomes research to reduce cancer incidence or promote early detection. Competitive renewal applications accepted.